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This has been my experience taking 2500 IU of vitamin D a day. I have stopped taking vit D since experiencing severe symptoms. I will keep you up to date if I figure out more. I will also have blood test done. Please make your own research. I am not a doctor. This is just what I believe has caused my problems. Symptoms include: muscle pain, fatigue – tired, bone weakness, nausea, vomiting, constipation, heart palpitation – arrhythmias, kidney stones, kidney pain.