Mystery Solved – Children Have Better Immune System. AstraZeneca Had Two Severe Events
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Children produce more IL-17A and IFN-gamma that results in better virus handling at the innate arm of the immune system stage. Adults on the other hand have more vigorous response from the adaptive arm. This in turn leads to better virus handling in children than adults.
Study
T-Helper 17 cells produce IL-17 (and more cells produce this cytokine as well.)
CD161+ cells are memory cells
IL-17A and IFN-gamma producing cells (TH1/TH17)
Innate lymphoid cells
AstraZeneca have two patients with transverse myelitis
