An adaptation of a lecture I gave my second year medical students. My selected references didn’t show on screen, so here they are:
Epidemiology and demographics
COVID-19 Provisional Counts – Weekly Updates by Select Demographic and Geographic Characteristics. Centers for Disease Control and Prevention (2020). Available at:
Zhu, N. et al. A Novel Coronavirus from Patients with Pneumonia in China, 2019: NEJM. New England Journal of Medicine (2020). Available at:
Al-Qahtani, A. A. Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2): Emergence, history, basic and clinical aspects. Saudi Journal of Biological Sciences (2020). Available at:
Andersen, K. G., et al. The proximal origin of SARS-CoV-2. Nature News (2020). Available at:
Libby, P. & Luscher, T. COVID-19 is, in the end, and endothelial disease. European Heart Journal (2020). Available at:
Johns Hopkins Coronavirus Resource Center (2020). Available at:
Pathophysiology of COVID-19
Ackermann, M. et al. Pulmonary Vascular Endothelialitis, Thrombosis, and Angiogenesis in Covid-19: NEJM. New England Journal of Medicine (2020). Available at:
Dasgupta, A. Is a Bradykinin Storm Brewing in COVID-19? The Scientist Magazine® (2020). Available at:
Mason, R. J. Pathogenesis of COVID-19 from a cell biology perspective. European Respiratory Society (2020). Available at:
Smith, T. A Supercomputer Analyzed Covid-19 - and an Interesting New Theory Has Emerged. Medium (2020). Available at:
Wadman, M., et al. How does coronavirus kill? Clinicians trace a ferocious rampage through the body, from brain to toes. Science (2020). Available at:
Williams, S. Could Curbing Runaway Immune Responses Treat COVID-19? The Scientist Magazine® (2020). Available at:
Azer, S. A. COVID-19: pathophysiology, diagnosis, complications and investigational therapeutics. New Microbes and New Infections (2020). Available at:
Libby, P. & Luscher, T. COVID-19 is, in the end, and endothelial disease. European Heart Journal (2020). Available at:
COVID-19 diagnosis and management
Carfi, A., et al. Persistent Symptoms in Patients After Acute COVID-19. JAMA (2020). Available at:
Management of Patients with Confirmed Coronavirus Disease (COVID-19). Centers for Disease Control and Prevention (2020). Available at:
McIntosh, K. Coronavirus disease 2019 (COVID-19): Clinical features. UpToDate (2020). Available at:
COVID-19 Protocols. Brigham and Women’s Hospital COVID-19 Clinical Guidelines (2020). Available at:
Information for Healthcare Providers about Multisystem Inflammatory Syndrome in Children (MIS-C). Centers for Disease Control and Prevention (2020). Available at:
Information on COVID-19 Treatment, Prevention and Research. National Institutes of Health (2020). Available at:
Fotuhi, M., et al. Neurobiology of COVID-19. Journal of Alzheimer’s Disease (2020). Available at:
Mask use for prevention of SARS-CoV-2 transmission
Scientific Brief: Community Use of Cloth Masks to Control the Spread of SARS-CoV-2. Centers for Disease Control and Prevention Available at:
Boodman, E. et al. Study: Universal mask use could save 130,000 lives by February. STAT (2020). Available at:
Patient education
COVID-19 disease progression. Medmastery (2020). Available at:
