Nihal Altan-Bonnet: Beta-Coronaviruses use lysosomes for egress

““β-Coronaviruses use lysosomes for egress instead of the biosynthetic secretory pathway” is presented by Nihal Altan-Bonnet, director of the Laboratory of Host-Pathogen Dynamics at the National Hearth, Lung, and Blood Institute (NHLBI, US NIH). The work has been published as Ghosh, et al, Cell, 2020:
Following the presentation is a robust discussion, including topics such as what the findings might mean for EV release and macrophage-mediated antigen presentation, and how viral proteins inhibit lysosomal acidification.