How Vitamin D Lowers Mortality Rates Of Infections, Including COVID-19:
Part 1:
The impact of vitamin D on hospitalization and mortality rates from COVID-19.
Part 2:
The benefits you could achieve by increasing vitamin D levels to 125 nmol/L (50 ng/ml).
Part 3:
How vitamin D affects the immune system to lower mortality rates of infections, including COVID-19.
References:
Books:
1) Vitamin D: Physiology, Molecular Biology, and Clinical Applications, 2nd edition, Michael F. Holick.
2) Vitamin D, 4th edition, David Feldman, et al.
Articles:
1) The vitamin D–antimicrobial peptide pathway and its role in protection against infection
2) Suppression of Iron-Regulatory Hepcidin by Vitamin D
3) High-dose vitamin D3 reduces circulating hepcidin concentrations: A pilot, randomized, double-blind, placebo-controlled trial in healthy adults
4) Immunologic Effects of Vitamin D on Human Health and Disease
5) The Anti-Inflammatory Effects of Vitamin D in Tumorigenesis
6) Down-regulation of IL-8 by high-dose vitamin D is specific to hyperinflammatory macrophages and involves mechanisms beyond up-regulation of DUSP1
7) Vitamin D and inflammatory diseases
Genes, Vitamin D and COVID-19:
1) Five key genes linked to severe COVID-19 found, suggesting drug targets
2) Genetic mechanisms of critical illness in Covid-19
3) The Non-Genomic Actions of Vitamin D
4) Differential immunomodulatory effect of vitamin D (1,25 (OH)2 D3) on the innate immune response in different types of cells infected in vitro with infectious bursal disease virus
5) Dipeptidyl peptidase 9 (DPP9) in human skin cells
6) Correction of vitamin D deficiency facilitated suppression of IP-10 and DPP IV levels in patients with chronic hepatitis C: A randomised double-blinded, placebo-control trial
7) Interferon alpha gene expression and serum level association with low vitamin D levels in Egyptian female patients with systemic lupus erythematosus
Vitamin D and COVID-19 Death:
1) Vitamin D Insufficiency May Account for Almost Nine of Ten COVID-19 Deaths: Time to Act. Comment on: “Vitamin D Deficiency and Outcome of COVID-19 Patients”
2) Vitamin D Deficiency in COVID-19 Quadrupled Death Rate
Vitamin D and COVID-19 Hospitalization:
1) More than 80 percent of hospitalized COVID-19 patients had vitamin D deficiency: study
2) Vitamin D Status in Hospitalized Patients with SARS-CoV-2 Infection
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