Many long haulers show signs of autoimmune diseases but are they really developing an autoimmune disease? Understanding the origin of symptoms is essential to diagnosing and treating conditions more effectively. And in long haulers, autoantibodies seem to be the culprit for many of the symptoms.
Here, we present evidence of what is causing a subset of long haulers their symptoms, markers that can predict them, and potential treatments.
Sources:
Potential Autoimmunity Resulting from Molecular Mimicry between SARS-CoV-2 Spike and Human Proteins
https://www.mdpi.com/1999-4915/14/7/1415#:~:text=Molecular%20mimicry%20between%20viral%20antigens,ranging%20from%20asymptomatic%20to%20fatal.
The autonomic aspects of the post-COVID19 syndrome
https://pubmed.ncbi.nlm.nih.gov/35182777/#:~:text=Similarly%20to%20chronic%20fatigue%20syndrome,related%20disorders%2C%20and%20numerous%20more.
COVID-19: autoimmunity, multisystemicinflammation and autoimmune rheumatic patients
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8943223/#:~:text=Coronavirus%20disease%202019%20(COVID%2D19,%2DCoV%2D2)%20infection.
Circulating anti-nuclear autoantibodies in COVID-19 survivors predict long-COVID symptoms
https://pubmed.ncbi.nlm.nih.gov/36137590/#:~:text=Interpretation%3A%20Persistently%20positive%20ANAs%20at,role%20of%20autoimmunity%20in%20PASC.
Temporary autoimmunity
https://news.emory.edu/stories/2022/08/hs_covid_triggered_autoimmunity_31-08-22/story.html
explanation of autoimmunity and mechanisms
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8396528/
