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Good morning, I’m still reporting on the coup.
For a couple of weeks now, the Indian pharma community has been buzzing about clinical trials coming down the pike for a repurposed use for yet another older drug -ivermectin, to fight COVID-19 disease.
Now the results are starting to come in and ivermectin looks just as good as these sources predicted it would be.
Ivermectin is an anti-parasitic drug that is usually used to treat head lice, but now some scientists have found that it can kill off the COVID-19 disease in just two days.
If further studies continue to show efficacy, it will be yet another example of the unusual nature of this virus – that it can be disrupted by something as simple as sufficient levels of zinc in one’s bloodstream thanks to a decades-old anti-malaria remedy on the one hand, but an anti-parasitic on the other.
Ivermectin is currently being experimented with across the U.S. to the point where it is – like many other drugs – rapidly becoming in short supply.
But according to researchers at Broward Health Medical Center in Florida it is working wonders for physicians on the frontline of battling COVID-19 disease.
According to Broward’s Dr. Jean-Jacgques Rajter:
“If we get to these people early, and what I mean by that is if their oxygen requirements are less than 50 per cent, I’ve had nearly a 100 per cent response rate, they all improve, if they’re on more oxygen than that, then it becomes a little more varied, some people, they don’t respond anymore because they are too far advanced.”
Dr. Raiter says he is currently writing up his findings, but warned that it could take weeks to publish them:
“If I wait, every day that goes by is another day when lots and lots of people get very sick, go to ICU, many of them die and that could theoretically even be preventable and that’s why I thought it was so critically important to get this information out there.”
Another Broward researcher, Dr. Nirav Shah agreed that ivermectin has great potential:
“Finding a safe, affordable, readily available therapy like ivermectin, if it proves effective with rigorous evaluation, has the potential to save countless lives.”
Australian researchers at Melbourne’s Monash Biomedical Discovery Institute are investigating ivermectin as well, but in vitro – in other words, in a test tube. Researcher Dr. Kylie Wagstaff explained:
“We found that even a single dose could essentially remove all viral RNA by 48 hours and that even at 24 hours, there was a really significant reduction in it.”
According to these researchers, although the SARS-CoV-2 virus, is not a parasite, ivermectin treats it like it is one and blocks the viral RNA from invading healthy cells and that slows the virus from replication and gives the patient’s immune system time to catch up and fight it off.
Researchers at the University of Utah also found that ivermectin seems to work in critically ill patients:
“… critically Ill patients with lung injury requiring mechanical ventilation may benefit from … ivermectin.”
The lead author of the Univ. of Utah team, Dr. Amit Patel:
“We noted a lower mortality and reduced healthcare resource use in those treated with ivermectin.”
Despite the recent politically motivated attempts to tarnish the proven effectiveness of HCQs in the United States, the world’s second most populous nation, India, stands by hydroxychloroquine as their first-line treatment for mild to moderate COVID-19 disease, but they too are finding that ivermectin seems to work where nothing else has.
In India, 62-year-old Sherli Abraham contracted COVID-19 from a family who returned from a trip to Italy in early March with COVID-19. Since then, she has spent 48 days in the hospital. Despite 45 days of treatment, she couldn’t get two COVID-19 tests in a row showing the disease had been completely vanquished. The stubborn case finally came under the scrutiny of the District Medical Board. They suggested treatment with ivermectin. The first dose didn’t seem to help, but the second dose did, and so yesterday, she was finally released to go home.
Ivermectin has been around for long enough that it has a generic version as well, but both the brand version and the generic are currently sold out in the
