Supplements That Help Calm Nerve Pain
Certain nutrients can support nerve repair, improve circulation, and ease burning or tingling when used alongside standard care. You may not require all, please discuss with your Doctor prior to starting any supplement. Hereās what studies show about each one:
š§¬ Alpha-lipoic acid (ALA) ā Fights oxidative stress and improves nerve blood flow. IV ALA 600 mg daily for 3 weeks eased pain by over 60% in diabetic neuropathy. Oral 600 mg/day also helped burning and tingling, though results vary (PMID: 8786016; 39469366; 37933068).
š Methyl B12 (mecobalamin) ā The active form of vitamin B12 that restores myelin and supports axon repair. Improves symptoms and conduction velocity, especially when deficiency is present. Common dose 500ā1500 Āµg/day (PMID: 34337067; 24455309).
ā” Acetyl-L-carnitine (ALC) ā Supports mitochondria and nerve regeneration. At 1000 mg three times daily, it reduced pain and improved nerve fiber density in diabetic neuropathy. Avoid during or soon after neurotoxic chemotherapy (PMID: 15616239; 31118753; 23733756).
š Omega-3s (EPA + DHA) ā Reduce inflammation and may promote nerve healing. In diabetes, 1.8 g/day for 6 months improved nerve fiber length but offered modest symptom relief. May reduce chemo-related neuropathy risk (PMID: 33952620; 40990181).
š§ Magnesium ā Acts as a natural NMDA blocker that calms overactive nerves. IV magnesium showed pain relief in small trials; oral 200ā400 mg daily may help, especially if deficient. Avoid high doses with kidney issues (PMID: 21659058; 12393768).
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