NAD+, which naturally occurs in the body, can also be increased through diet, rather than supplementation. Some NAD+-boosting foods to include in your diet are cucumber, cabbage, edamame, broccoli, avocado, tomato, beef, shrimp and dairy.
As a supplement, NAD+ is available in oral, intravenous (IV) or intramuscular (IM) forms, notes Dr. Schraga. He advises taking NMN or NR, which are the most studied. Dr. Salzman recommends oral administration via capsules as the most viable and convenient way to achieve systemic levels of NAD+, as large-scale, human clinical trials on the effectiveness of direct NAD+ infusions or injections is limited.
The bottom line? While there’s no evidence that NAD+ reverses aging, there are several potential research-backed benefits, including improved sleep and increased energy levels and increased physical performance.
If you do choose to incorporate the supplement into your wellness routine, do so under the guidance of your health care provider. Dr. Salzman recommends complementing NAD+ with a balanced diet, adequate sleep, aerobic exercise and resistance training and proper stress management, which support overall health and longevity.