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Not all supplements are created equal. And, that’s hardly news.

The market is flooded with brands making bold health claims, and collagen is no exception. As a wellness writer, I’ve tried my fair share, and I’m often skeptical that I’ll see any real long-term difference in my hair, skin or nails. But if there’s one formula that’s catching my attention, it’s Elysium’s Cofactor.

This isn’t your ordinary collagen supplement. Cofactor blends clinically backed Premium Collagen Peptides, Hyaluronic Acid, Vitamin C and 250 milligrams of NR to support NAD+ levels — the coenzyme that biohacking enthusiasts have linked to cellular health and longevity. And right now, during Amazon’s Spring Sale, Cofactor is marked-down 35% off.

According to Elysium, Cofactor works by supporting your body’s natural ability to repair and maintain collagen — so it’s not just for hair, nails, skin elasticity and hydration, but also for overall vitality. Translation: internal and external benefits.

Reviewers are seeing the results, with one calling it the best collagen supplement they’ve tried. And that was just after the first month of use.

cofactor supplement Amazon

“My skin feels noticeably more hydrated and has a healthy glow that wasn’t there before,” the reviewer shared, adding that they love that it combines collagen peptides with NAD+.

The unflavored powder blends easily into any cold liquid, and each pouch contains 28 daily servings for a full month of support. According to Elysium, consistent use can lead to enhanced skin hydration within weeks and smoother skin with fewer visible wrinkles over time. Some users report benefits even sooner.

“It feels like I’m supporting my skin and overall wellness at the cellular level,” they added. “After just a few weeks, I’ve also noticed my joints feel less stiff, especially in the mornings.”

Your Amazon Big Spring Sale FAQs, answered

What is Big Spring Sale?

This annual Amazon Spring Sale offers deep discounts on bestsellers and everyday essentials. The seasonality of the sale makes it prime (pun intended) for savings on outdoor products, spring cleaning needs, tools and home essentials, plus all the great discounts you’ve come to expect from a Prime Day-like event.

How long is Big Spring Sale?

Amazon’s Big Spring Sale is a marathon compared to the retailer’s shorter deal events. Shoppers can take advantage of seasonal discounts running from Wednesday, March 25 through Tuesday, March 31.

Do you have to be an Amazon Prime member to shop?

Unlike Prime Day in July, this event is open to everyone who shops on Amazon. However interested shoppers can grab a 30-day free trial to try Prime, and its many benefits with no strings attached, and gain access to exclusive deals, special “Prime” badges on select items and the added convenience of fast, free shipping.

What are the best deals?

From reporting on Amazon sales for years, we can tell you for certain that Big Spring Sale is the ideal period to stock up on household essentials, refill your skincare empties, save on the best vacuums to save your spring cleaning projects, and comb through the massive catalog of Amazon best-sellers.

Is it worth it?

We certainly think so! Big Spring Sale is a great chance to score deals on thousands of best-sellers, seasonal favorites, big-ticket tech and appliances and every day essentials. Our team diligently sorts through all the offers to find you the very best items to grab on sale.

When is the next Prime Day?

Already wondering when Amazon’s next Prime Day is? Prime Day takes place in July each year, so it’s safe to assume it will take place in mid-July 2026 — similar to previous years.

Don’t miss Post Wanted’s around-the-clock coverage. Click here to find all of the best deals.

This article was written by Miska Salemann, New York Post Commerce Writer/Reporter. As a health-forward member of Gen Z, Miska seeks out experts to weigh in on the benefits, safety and designs of both trending and tried-and-true fitness equipment, workout clothing, dietary supplements and more. Taking matters into her own hands, Miska intrepidly tests wellness products, ranging from Bryan Johnson’s Blueprint Longevity Mix to the viral Oura Ring to Jennifer Aniston’s favorite workout platform – often with her adorable toddler by her side. Before joining The Post, Miska covered lifestyle and consumer topics for the U.S. Sun and The Cannon Beach Gazette.