Remdesivir Mechanism of Action
Note: Remdesivir is an adenine analog and not uracil. I taught it as a Uracil analog.
MERS-COV peaks in humans between 7-10 days after the onset of symptoms. This gives a good chance to use Remdesivir.
Early therapy with Remdesivir will help reduce the virus load and the damage due to the immune response.
Mechanism of action
Adenosine nucleotide analog
SARS-COV and MERS-COV pathophysiology
Clinical Trial of Remdesivir to Treat COVID-19 Begins
Improvement observed in 68% of the patients
Remdesivir clinical trials
Inconclusive yet hopeful results
Another study finds the drug with high death rate and more side effects