Remdesivir Mechanism of Action

Note: Remdesivir is an adenine analog and not uracil. I taught it as a Uracil analog.

MERS-COV peaks in humans between 7-10 days after the onset of symptoms. This gives a good chance to use Remdesivir.
Early therapy with Remdesivir will help reduce the virus load and the damage due to the immune response.

Mechanism of action

Adenosine nucleotide analog

SARS-COV and MERS-COV pathophysiology

Clinical Trial of Remdesivir to Treat COVID-19 Begins

Improvement observed in 68% of the patients

Remdesivir clinical trials

Inconclusive yet hopeful results

Another study finds the drug with high death rate and more side effects