Can niacin help immune activation in people living with HIV (who are on antiretroviral therapy)?
Principal Investigator Dr. Bertrand Lebouché explains.
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Niaspan® is an extended-released form of niacin, which also known as vitamin B3.
The researchers will examine the ability of an oral form of extended-release niacin to reduce immune activation and increase CD4 cells in persons with sub-optimal immune responses despite sustained virologic suppression from antiretroviral therapy.
Study researchers believe that by regulating an amino acid called tryptophan, niacin may decrease T cell immune activation which may enhance CD4 recovery and improve brain functions.
The study is enrolling 20 participants in Montreal.
CIHR Canadian HIV Trials Network
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