Lu Lu, from Fudan University in Shanghai, and Jang Shibo, from the New York Blood Centre, joined the living virus, which is officially known as Sars-CoV-2, on laboratory-grown T lymphocyte cell lines. They do this by capturing a cell infected by a virus, bore a hole in its membrane and inject toxic chemicals into the cell. These chemicals then kill both the virus and infected cell and tear them to pieces. To the surprise of the scientists, the T cell became a prey to the coronavirus in their experiment.
They found a unique structure in the virus’s spike protein that appeared to have triggered the fusion of a viral envelope and cell membrane when they came into contact. The virus’s genes then entered the T cell and took it hostage, disabling its function of protecting humans. The lower the T cell count, the higher the risk of death.
SCMP
