Coronavirus (COVID-19) and the Role of Vitamin D | Immune System and Vitamin D | How Much Vitamin D Do You Really Need?
Coronavirus (COVID-19) cytokine storms increases mortality and if vitamin D plays a role in decreasing pro-inflammatory cytokines, this video explores could vitamin D deficiency increase the susceptibility for a Coronavirus (COVID-19) patient developing cytokine storms?
Vitamin D is a fat-soluble vitamin that plays a role in calcium absorption, bone health and immune function. Vitamin D comes in two forms: vitamin D3 which we get from sunlight and animal products and vitamin D2 through our diet like milk, fish and fortified cereals. Vitamin D supplements can come in either vitamin D2 or D3 and while some experts have suggested vitamin D3 is more potent and absorbed better, either type is ok if taking it for general health.
Vitamin D2 mainly comes from fortified foods like breakfast cereals, milk, and other dairy items. Vitamin D3 is made by your own body when UVB light from the sun penetrates 7-dehydrocholesterol in the skin. Vitamin D3 is also found in some foods, including eggs and fatty fish, such as salmon, tuna, and mackerel.
Both Vitamin D2 and D3 are then bound to a carrier protein called vitamin D binding protein (DBP) and then metabolized in the liver into calcifediol, also called 25-hydroxyvitamin D. When your doctor orders lab tests to check your vitamin D levels, they are measuring your 25-hydroxyvitamin D levels.
Vitamin D status is significantly associated with clinical outcomes. The results suggest that an increase in serum 25 hydroxyvitamin D level in the body could either improve clinical outcomes or mitigate worst (severe to critical) outcomes, while a decrease in serum 25 hydroxyvitamin D level in the body could worsen clinical outcomes of COVID-2019 patients. In conclusion, this study provides substantial information to clinicians and health policy-makers. Vitamin D supplementation could possibly improve clinical outcomes of patients infected with COVID-19.
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