Genetics plays a significant role in immunity along with non-heritable factors, including nutrition and activity level. Individual variations in genes, known as single nucleotide polymorphisms, or SNPs, might influence how a person responds to a viral infection. Various SNPs impact how the virus enters the host cell, how it replicates and how the host responds. Genetically low plasma vitamin D levels are associated with higher mortality from respiratory infections, and SNPs in the vitamin D receptor that are associated with a higher risk of respiratory tract infections might play a role. In this clip, Dr. Rhonda Patrick discusses the role that genetics plays in the immune system.
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