Vitamin K2 MK7 Review and Benefits for Teeth and Dental / Bone / Artery and BRAIN HEALTH! Between 100-1,000mcg per day is considered a standard dose.
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On a nutrition label, vitamin K1 and vitamin K2 are both simply listed as vitamin K, even though our bodies don’t treat them identically. Vitamin K1 and K2 share the same chemical ring structure but have varying side chain lengths. (2) Vitamin K1, found in vegetables like leafy greens, has a monounsaturated tail with four carbon groups. Vitamin K2 forms have polyunsaturated tails with anywhere from four to 11 carbon groups and are called menaquinones, MK-4 through MK-11. MK-4 is found mostly from animal sources, while fermented vegetables are the main source of MK-7.
Vitamin K is a cofactor of the enzyme vitamin K carboxylase. In short, vitamin K helps add a carbon dioxide to a protein, giving it a negative charge and thereby allowing it to bind to positively charged calcium. Vitamin K1 is preferentially used by the liver to activate blood-clotting proteins. The “K” originally stood for “koagulation.” Vitamin K2, on the other hand, is primarily used in other tissues to ensure that calcium is deposited where it should be, such as bone and cartilage, and to prevent calcium from accumulating where it shouldn’t, like blood vessels and kidneys.
Millions of people take calcium supplements to maintain healthy bone. Yet few patients or physicians realize that optimizing bone integrity involves more than taking a single mineral supplement. A critical additional component for bone and cardiovascular health is vitamin K2.
Recent research has revealed that, without vitamin K2, calcium regulation is disrupted. In fact, low levels of vitamin K2 are associated with an increased risk of heart disease and atherosclerosis.1 Astute doctors have long known that people with a lack of calcium in their bones are more likely to possess an excess of calcium in their arteries, and vice versa. The resulting lack of calcium in bone leads to osteoporosis, while the deposition of calcium in the arterial wall leads to coronary heart disease and other manifestations of cardiovascular, renal, and neurodegenerative disease.
Although vitamin K has been around for decades, dietary recommendations have been overshadowed by the nominal amount required for healthy blood clotting—and have ignored the optimal amounts of vitamin K needed to maintain healthy bones and arteries. In this article, we’ll explore how vitamin K2 regulates calcium as well as the recent evidence supporting this unique vitamin in preventing heart disease and osteoporosis as well as certain types of cancer.
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