More at

Michael: Can taking a bunch of vitamin D on its own become problematic?

Kiran: Yeah absolutely, there’s a condition called hypervitaminosis D. That is basically vitamin D toxicity. And when you look at the clinical pathology of what vitamin D toxicity looks like, it is exactly the same as vitamin K2 deficiency. So what happens is when you take a lot of vitamin D without K2, you are causing the release of a lot of osteocalcin, and other vitamin K dependent proteins as well, and you’re using up your bodies’ any storage, or any amount of vitamin K2 that your body has. Now once you’ve used up your vitamin K2 and you’ve depleted it down to a clinically deficient level, you start to get calcification in all the areas where you don’t want. So calcium starts to settle in on your soft tissues in your arteries, in your tendons and even in your skin and your subdermal layers. So you start to get hypercalcification everywhere. So when you look at vitamin D toxicity, vitamin D toxicity is characterized by hypercalcification in the body. And that’s the same thing as vitamin K2 deficiency. So what you’re doing when you take a whole bunch of vitamin D without taking K2 you’re causing more calcification at the end of the day than causing benefit.