As the delta variant becomes the dominant strain of the Covid-19 pandemic, scientists are working to understand the role variants will play in future surges of Covid-19, the efficacy of current vaccines, and how long immunity will last. Dr. Shane Crotty,, virologist and professor in the Center for Infectious Disease and Vaccine Research at the La Jolla Institute for Immunology (LJI), provides insights on the progress of Covid-19 vaccine immunity research for current U.S. Covid-19 vaccines (Pfizer, Moderna, Janssen/Johnson & Johnson), and critical emerging questions, such as the impact of the delta variant on the efficacy of current Covid-19 vaccines.