2026 is officially the UK’s ‘Year of Treatment-Stacked Skin Investment’, with the global regenerative medicine market projected at USD 4.19 billion and the non-invasive segment expected to grow in double digits.
At the centre of this shift are bio-stimulators such as polynucleotides, exosomes, Sculptra, and Radiesse. These treatments work with the body rather than against it, stimulating natural collagen production for gradual, biologically harmonious results. Treatment stacking is a strategic combination of polynucleotides and long-acting bio-stimulators to address multiple layers of the skin simultaneously.
“The aesthetic landscape has fundamentally shifted towards regenerative treatments that work with the body’s natural processes”, says Dr Stephen Hennessy, Founder of Dr Hennessy Cosmetic Clinics.
“Bio-stimulators strengthen skin from within, providing texture, firmness and structure over months, not days. Newer offerings like polynucleotides and exosomes make subtle improvements in tone and hydration. Sculptra, proven over twenty years, has resurged for its ability to rebuild the skin’s barriers with long-lasting results. Radiesse, diluted to build collagen instead of adding instant volume, matches today’s patients’ needs of gradual, lasting change. As these treatments gain their value in patients’ thoughts again, we have witnessed a 43% uplift in demand at the clinic in 2025”, he adds.
Kerry Hennessy, Dr Hennessy’s wife and long-standing collaborator in the clinic, brings a rare dual perspective, combining lived experience as a patient with an intimate understanding of the precision that underpins the clinic’s approach to ageing well.
Rather than opting for quick, visible fixes, Kerry has herself chosen to invest in a long-term, regenerative approach to ageing. In line with the growing trend towards treatment stacking, Kerry is also combining Sculptra with Radiesse to address crepiness and skin laxity in areas such as the neck and arms, zones that Dr Hennessy notes are being increasingly prioritised by patients seeking all-around rejuvenation.
“I’m not trying to look younger, just like the best version of me,” Kerry Hennessy explains.
She is currently following a structured course of Sculptra, which includes a collagen-stimulating protocol designed to gradually firm the skin. Often described as an investment treatment, Sculptra works over time, gradually firming the skin and restoring the underlying face structure, encouraging the body’s own collagen production rather than relying on instant volume.
With one session recommended per decade of life, Kerry’s four-month programme reflects a conscious commitment to long-term skin health and a noteworthy shift across Dr Hennessy’s clinics, where patients increasingly choose layered, biostimulatory treatments. As patients adopt more informed steps for skin health, 2026 marks a shift where aesthetics become less about correction and more about long-term investment.
