Georjon, H. & Bernheim, A. The highly diverse antiphage defence systems of bacteria. Nat. Rev. Microbiol. 21, 686–700 (2023).
Bernheim, A., Cury, J. & Poirier, E. Z. The immune nodules conserved across the tree of life: towards a definition of ancestral immunity. PLoS Biol. 22, e3002717 (2024).
Cury, J. et al. Conservation of antiviral systems across domains of life reveals immune genes in humans. Cell Host Microbe 32, 1594–1607.e5 (2024).
Tobiasson, V., Luo, J., Wolf, Y. I. & Koonin, E. V. Dominant contribution of Asgard archaea to eukaryogenesis. Nature https://doi.org/10.1038/s41586-025-09960-6 (2026).
Eme, L. et al. Inference and reconstruction of the heimdallarchaeial ancestry of eukaryotes. Nature 618, 992–999 (2023).
Leão, P. et al. Asgard archaea defense systems and their roles in the origin of eukaryotic immunity. Nat. Commun. 15, 6386 (2024).
Jenson, J. M. & Chen, Z. J. cGAS goes viral: a conserved immune defense system from bacteria to humans. Mol. Cell 84, 120–130 (2024).
Gao, L. A. et al. Prokaryotic innate immunity through pattern recognition of conserved viral proteins. Science 377, eabm4096 (2022).
Iranzo, J., Cuesta, J. A., Manrubia, S., Katsnelson, M. I. & Koonin, E. V. Disentangling the effects of selection and loss bias on gene dynamics. Proc. Natl Acad. Sci. USA 114, E5616–E5624 (2017).
Tesson, F. et al. A comprehensive resource for exploring antiphage defense: DefenseFinder webservice, wiki and databases. Peer Community J. 4, e91 (2024).