COVID-19 Critical Care Update with Maurizio Cecconi, MD of Humanitas University in Milan and Derek C. Angus, MD, MPH of the University of Pittsburgh. Recorded on June 8, 2020.
Topics discussed in this interview:
1:34 Anything new about epidemiology of COVID-19? What’s the major risk characteristics, risk factors? What’s the mortality look like in the intensive care unit?
4:33 What is the mortality rate in the ICU run by Dr Angus in Pittsburgh?
5:58 Is smoking or asthma is protective?
11:45 Where are we on respiratory support? High-flow oxygen, prone positioning, preventing intubation? Is early intubation better than late intubation?
14:52 Prone positioning prior to intubation?
16:23 Approach to respiratory support
21:22 Are there phenotypes and should phenotypes drive therapy? (Treatments)
30:13 Is it going to take more than one drug to really reduce mortality? Is it convalescent plasma and steroids? Is it Tocilizumab and steroids?
33:13 Do you think it’s some form of two drugs? Is it earlier treatment with some drug regimen?
35:19 Convalescent plasma as a treatment as compared to Remdesivir?
37:19 Does the morbidity associated with COVID-19, following being in the ICU look different to you than any other frail, elderly individual who is in the ICU and is either intubated or not? Do they need a different type of post-ICU care?
42:17 From a critical care standpoint, what have been the biggest surprises from this pandemic? What scientific questions do we still need to answer?
50:27 Closing notes
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