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The Efficacy of Alpha-Lipoic Acid and B Vitamins in the Management of Diabetic Patients with Symptomatic Distal Symmetric Polyneuropathy: A Randomized Controlled Trial

Abstract Background Distal symmetric polyneuropathy (DSPN) is a microvascular complication of diabetes that significantly impairs quality of life. However, effective treatment of symptomatic DSPN remains a challenge. This study investigates the efficacy of a fixed-dose combination of alpha lipoic acid…