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Supplements are marketed as a good way to combat a range of health issues and reap benefits like better sleep, lower stress, weight loss, and more. However, it’s crucial to remember that these products aren’t miracles—in fact, they’re often far less effective than advertised, and in some cases, they can even be dangerous. In high doses, the wrong supplements can come with downsides that far outweigh the benefits.

To highlight a few potentially dangerous supplements that it’s crucial to exercises caution while taking, we gathered insight from health experts HaVy Ngo-Hamilton, Pharm.D.; Jesse Feder, RDN, CPT, registered nutritionist; and Dr. Charles, who shared a TikTok on the matter. Find all of their expert advice below.

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1. Kava can damage your kidney and liver

Kava is a popular anti-stress supplement that many people consume in order to bring a sense of calm to their brain and body. “Kava, which is typically consumed as a tea, is a supplement known to promote relaxation,” Feder explains.

Unfortunately, though, this relaxation could come with a risk; “Consuming kava regularly has been shown to affect enzyme and antioxidant activity in the liver which can lead to liver damage.” Yikes!

It’s best to practice other stress-relieving habits, rather than turning to kava.

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2. Vitamin A can damage your liver

Dr. Charles warns viewers about the popular belief that Vitamin A supplements can work wonders for the skin and eyes. Although Vitamin A is certainly an important nutrient, he highlights a darker side to excessive Vitamin A intake, which could be a result of supplementation.

“People think it can help your skin and eyes, but it can actually build up in your body and cause liver damage,” he cautions. While Vitamin A is essential for maintaining healthy skin and vision, excessive amounts from supplements can indeed lead to toxicity, affecting the liver and causing a range of health issues. Instead, it’s best to get this vitamin directly from the foods you eat.

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3. Excessive Vitamin D and Calcium can damage your heart

Deficiencies in vitamin D and calcium are prevalent, often stemming from inadequate sun exposure. Consequently, many turn to supplements to meet their nutritional needs. However, excessive intake of these nutrients may heighten the risk of cardiovascular diseases.

HaVy Ngo-Hamilton warns, “Too much vitamin D and calcium can increase the risk of cardiovascular diseases, especially if these supplements are purchased from non-credible sources.”

Before incorporating these supplements into your routine, it’s crucial to consult with your healthcare provider and assess your blood levels to determine if supplementation is necessary. When in doubt, getting these nutrients straight from the foods you eat is your best bet.