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NEW ORLEANS (WGNO) — Papaya is trending for digestion, gut health and “debloating.” But how we use it makes all the difference – and whether it’s ripe or green, seeds or supplement form. In Wednesday’s FUELED, we’ve got the rundown on the benefits of each, and what lives up to the buzz.

What is papaya?

Contains papain — a digestive enzyme that helps break down protein

Functions very differently depending on ripeness:

ripe → sweet fruit, yellow-orange flesh

green → firm, savory, functional ingredient

Ripe Papaya

Soft, orange flesh, naturally sweet; ~8–11 grams sugar per cup

Provides vitamin C, fiber, hydration

Papain is present, but less than green papaya – lower enzyme activity once fully ripe

Simple ways to use: fresh with lime; yogurt or smoothies; paired with savory dishes

Green Papaya (Unripe)

Green skin, firm texture, not sweet; Very low sugar (~2–3 grams per cup)

Used like a vegetable (slaws, salads, stir-fries)

Highest papain activity in green papaya

As papaya ripens, papain activity drops significantly

Functional use: mash and use in marinades

helps break down protein in tougher cuts of meat

Use small amounts, short time:  ~30–60 minutes; too long → overly soft texture

Papaya Seeds

Edible, peppery flavor. Use it dried and ground as a pepper substitute; blended into dressings

Papain – Digestive Enzyme, Available in Supplement Form

Concentrated digestive enzyme from papaya

May help with heavy or high-protein meals; may also help with feelings of bloating

Papaya: Key Takeaways

Ripe papaya → hydration, vitamin C, fiber

Green papaya → culinary use + strongest enzyme activity

Seeds → flavor, not a significant source of enzymes, compared to green flesh

Supplements → targeted digestive enzymes

Papaya can support digestion — but overall diet still matters most

FUELED WELLNESS + NUTRITION IS POWERED BY EVAMOR | Learn more at evamor.com.

Molly Kimball, RD, CSSD is a registered dietitian and nutrition journalist in New Orleans, and founder of the Ochsner Eat Fit nonprofit restaurant initiative. Tune in to her podcast, FUELED | Wellness + Nutrition, and follow her on Facebook, Instagram, and Twitter at @MollyKimballRD. Download the Eat Fit mobile app to stay in the know about Eat Fit partners, new dishes, festivals, and more. To schedule a nutrition consult with Molly’s Lifestyle Nutrition team, email nutrition@ochsner.org.

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