For COVID-19, pregnant individuals remain one of the least vaccinated groups in the US, especially concerning with increased risks of pregnancy complications due to COVID-19, including hospitalization and preterm birth, which are preventable with vaccination. In addition, a newborn’s immune system is not fully developed, but some vaccines received during pregnancy could protect an infant in early life. This is because some maternal antibodies can pass through the placenta to the fetus, and through breast milk to the infant. Boosting immunity in newborns through such transfer of antibodies has received increased attention in light of the COVID-19 pandemic.
Links to source references are embedded in the transcript at https://ja.ma/3JzrMxq.
To learn more, listen to a related podcast at https://ja.ma/3oT7WFJ, read a JAMA Medical News story on COVID-19 vaccines and infertility myths at https://ja.ma/3rSCucm, and read a JAMA patient page on COVID-19 and pregnancy at https://ja.ma/34W4AdP.
Topics discussed in this video:
0:00 What is passive immunity
1:15 Exclusion from clinical trials
1:44 Recommendations from CDC and medical organizations
2:11 Vaccine safety and efficacy in pregnancy and lactation
3:02 Data on passively-transferred antibodies
4:21 Unanswered questions
4:42 Vaccine hesitancy
5:30 Importance of vaccination for pregnant individuals
6:14 Increased risks of COVID-19 in pregnancy
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